Study of serum adiponectin levels for early detection of type 2 diabetes mellitus and its complications on kidney

Background: Type 2 diabetes mellitus is a chronic metabolic disorder due to insulin resistance caused by destruction of beta cells pancreas. Insulin in newly diagnosed type patients leads hyperglycemia. Serum adiponectin more sensitive and specific biomarker for early detection diabetic nephropathy than urinary microalbuminuria.Methods: This case-control study conducted Akash Institute Medical Sciences, A total 180 subjects (120 cases 60 controls). All the included after informed consent, blood samples urine are collected from all subjects. The serum Adiponectin was estimated using enzyme-linked immunoassay (ELISA) fasting sugar (FBS), post prandial (PPBS) renal function test (RFT) also laboratory standard methods.Results: evaluated FBS, PPBS, RFT levels with compare them healthy controls. significantly elevated compared found that PPBS controls, statistically significant when controls (p= 0.0001).Conclusions: suggesting s estimation useful nephropathy. Because mellitus, this positively correlated FBS PPBS.